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Do NICE tables overestimate the prevalence of significant CAD?

June 2014 Br J Cardiol 2014;21:75 doi:10.5837/bjc.2014.017

Do NICE tables overestimate the prevalence of significant CAD?

Jaffar M Khan, Rowena Harrison, Clare Schnaar, Christopher Dugan, Vuyyuru Ramabala, Edward Langford

Abstract

Introduction There is no universal definition for stable angina, as there is for acute coronary syndrome.1 The diagnosis may be based on clinical history alone or on clinical history supplemented by functional testing, or angiography, or both. Angina pectoris is most often due to obstruction to flow in the epicardial coronary arteries, and the ‘gold-standard’ investigation, to date, to detect this, has been invasive coronary angiography.2 A small proportion of patients may have angina with unobstructed coronary arteries secondary to either microvascular coronary disease or coronary spasm.3 Functional ischaemia is not routinely tested for

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