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Tag Archives: renin-angiotensin-aldosterone system

August 2018 Br J Cardiol 2018;25:97–101 doi:10.5837/bjc.2018.025

Impact of hyperkalaemia in managing cardiorenal patients – a healthcare professional perspective

Navneet Kalsi, Sarah Birkhoelzer, Philip Kalra, Paul Kalra

Abstract

Introduction Modulation of the RAAS is an integral part of the management for patients with chronic heart failure, prior myocardial infarction and diabetic nephropathy. Evidence from large scale trials demonstrates the clear prognostic benefit of angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers, mineralocorticoid receptor antagonists and more recently angiotensin receptor neprilysin inhibitors for these high-risk groups.1-3 The use of these agents, particularly in combination, can be associated with hyperkalaemia, although the incidence is unknown.4 A clear trend exists between the development of hyperkalaemia and

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News from the 7th Annual Scientific Meeting of the Cardiorenal Forum

December 2012 Br J Cardiol 2013;20:20–1 Online First

News from the 7th Annual Scientific Meeting of the Cardiorenal Forum

Abstract

Introduction As doctors and scientists we are accustomed to breaking down problems and simplifying complex pathology in order to focus our management and identify possible targets for future therapies. The pathophysiology of cardiorenal disease is no different but, as yet, attempts to elucidate the complex interaction between heart and kidneys has failed. Although cardiac and renal disease are often diagnosed together, it is clear that a straightforward causal relationship does not exist. Disease in either serves as a risk factor for disease in the other and perpetuates the progression of that disease, but why this is so is unclear. Whilst th

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