Tag Archives: sitagliptin

Cholesterol lowering significantly reduces stroke in the elderly Use of cholesterol lowering drugs (statins and fibrates) is associated with a one third lower risk of stroke in older adults without previous disease, finds a study published in the BMJ. A research team based in France set out to determine the association between use of lipid-lowering drugs in healthy older people and long-term risk of coronary heart disease and stroke. They tracked 7,484 men and women (average age 74 years) with no known history of vascular events, such as heart attacks and strokes, living in three French cities (Bordeaux, Dijon and Montpellier). After an aver

This image of Tetralogy of Fallot has won Carol Young, a radiographer at Great Ormond Street Hospital, London, an award for the best image quality and lowest radiation dose in the Siemens Healthcare International CT Image Contest. She beat 627 other entries from 43 countries Sitagliptin licence in renal disease Sitagliptin (Januvia®, MSD) has received a licence in the UK for use in people with type 2 diabetes with moderate to severe renal impairment. The licence follows data from two clinical studies. In one study comparing sitagliptin (25 mg or 50 mg once daily) with glipizide (2.5 to 20 mg once daily) in patients with type 2 diabetes and

NICE updates A new ‘Evidence Update’ has been produced by the National Institute for Health and Clinical Excellence (NICE), which summarises selected new evidence relevant to the NICE guideline on the management of chronic heart failure (CHF) in adults in primary and secondary care (clinical guideline 108).NICE says “Whilst Evidence Updates do not replace current accredited guidance, they do highlight new evidence that might generate a future changes in practice.”  It says it will welcome feedback from societies and individuals in developing this service. The update is available from www.evidence.nhs.uk/evidence-update-2. New guides

Coffee consumption shows CHD benefits in women A meta-analysis of a number of cohorts studies published in the International Journal of Cardiology (2009;137:216-25) demonstrates that habitual coffee consumption may be associated with a lower risk of coronary heart disease (CHD) in women. Analysis of data from 21 cohort studies showed that moderate coffee consumption (of up to four cups of coffee per day) were associated with a 18% reduction in risk of CHD in women.  The investigators note that such an effect was unlikely to be caused by chance. Further benefits have been shown from a meta-analysis published in the Archives of Internal Medici