March 2010 Br J Cardiol 2009;17(Suppl 1):S10-11
Ranil de Silva
Dual antiplatelet therapy for all CVD patients? Table 1. Currently used antiplatelet drugs Currently used antiplatelet drugs are summarised in table 1 and pivotal clinical trials of dual antiplatelet therapy in table 2. The Clopidogrel for High Atherothrombotic Risk and Ischaemia Stabilisation, Management and Avoidance (CHARISMA) trial2 is the only prospective randomised clinical trial to evaluate the efficacy and safety of dual antiplatelet therapy in all CVD patients. Initiated after the Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events (CAPRIE) trial had shown a 9% relative risk reduction with clopidogrel compared w
November 2009 Br J Cardiol 2009;16:269-71
BJCardio editorial staff
This new report from ECASS 3 was published online on October 21st in Lancet Neurology. The authors, led by Dr Werner Hacke (Ruprecht-Karls-Universität, Germany) report that although not all end points were statistically significant, there was “a clear pattern in favour of alteplase”. In the ECASS 3 trial, 821 stroke patients presenting 3-4.5 hours after symptom onset were randomised to alteplase (in the approved regimen of 0.9 mg/kg body weight) or placebo. The primary end point was disability at 90 days, and this was judged by a favourable or unfavourable outcome on the modified Rankin Scale. Results showed that significantly more pati
September 2007 Br J Cardiol 2007;14:190
Deepak L Bhatt, P Gabriel Steg
In this larger context, the international Reduction of Atherothrombosis for Continued Health (REACH) Registry was launched in order to study outcomes of atherothrombotic disease, risk factors for atherothrombosis, and also current treatment patterns. Already, the REACH Registry has provided insights at a global level.1 For example, under-treatment of common risk factors such as hypertension, hyperlipidaemia, and diabetes was observed in all regions included in the REACH Registry. Obesity, including morbid obesity, was highly prevalent. Multivascular disease – atherothrombosis affecting more than one arterial territory – was present in app
November 2006 Br J Cardiol 2006;13:386-90
BJCardio editorial team
No content available
July 2005 Br J Cardiol 2005;12:308-11
Michael Kirby
No content available
January 2005 Br J Cardiol 2005;12:53-6
Mushtaq Wani, Ranjini Navaratnasingam
No content available
November 2004 Br J Cardiol 2004;11:479-82
Mitchell M Lindsay, Keith G Oldroyd
No content available
July 2004 Br J Cardiol 2004;11:315-20
Michael Kirby, Rubin Minhas
No content available
November 2003 Br J Cardiol 2003;10:478-81
Mike Mead
No content available
May 2003 Br J Cardiol 2003;10:197-205
Matthew Walters, Jacqueline Taylor, Adrian Brady
No content available
You need to be a member to print this page.
Find out more about our membership benefits
You need to be a member to download PDF's.
Find out more about our membership benefits