Myocardial infarction in a patient with hypertrophic cardiomyopathy

Myocardial infarction in a patient with hypertrophic cardiomyopathy Hypertrophic cardiomyopathy (HC) is a disease characterised by marked heterogeneity in its morphology and natural history. The prevalence of significant coronary artery disease in this population has been estimated to be just over 10%.1 On the other hand, the prevalence of transmural myocardial infarction in the absence of significant coronary atherosclerosis is about 15% in a population of patients who have died from HC.2 Although electrocardiographic criteria for diagnosis of acute myocardial infarction (AMI) in adults are well known and accepted, no general criteria exist for diagnosis of AMI in patients with HC. Further, there are no clear-cut guidelines for the management of patients with HC who present with a suspected AMI.