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Tag Archives: acute coronary syndromes

Dual antiplatelet therapy following acute coronary syndromes: optimal regimens and duration of therapy

September 2017 Br J Cardiol 2017;24(suppl 1):S10–S15 doi:10.5837/bjc.2017.s02

Dual antiplatelet therapy following acute coronary syndromes: optimal regimens and duration of therapy

Wael Sumaya, Robert F Storey

Abstract

Background Thrombus formation in the coronary tree is the principal cause of acute coronary syndromes (ACS).1 Following plaque rupture or erosion, platelets adhere to exposed ligands (collagen, von Willebrand factor [vWF]) under high-flow conditions and this leads to platelet activation. Following platelet adhesion and activation, multiple agonists are secreted, including thromboxane A2 (TXA2) and adenosine diphosphate (ADP). TXA2 further activates platelets and ADP amplifies and sustains platelets’ activation, particularly through platelet P2Y12 receptors.2 In view of the pivotal role of platelets in arterial thrombosis, blocking TXA2 pro

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Chronic stable angina guidelines – is there an emerging international consensus?

August 2012 Br J Cardiol 2012;19(Suppl 2):S2–S11 doi:10.5837/bjc.2012.s06

Chronic stable angina guidelines – is there an emerging international consensus?

Professor Jose Lopez-Sendon, Dr Henry Purcell, Professor Paolo Camici, Dr Caroline Daly, Professor Jamil Mayet, Dr John Parissis, Professor Francesco Pelliccia, Professor Christophe Piot, Professor Rainer Hambrecht

Abstract

Introduction Stable angina is the most common manifestation of coronary heart disease. While considered relatively benign in terms of prognosis, the condition confers a higher risk of cardiovascular events than in the general population, with average annual mortality rates of 1–2%. Guidelines for the management of stable angina are relatively conservative in their approach, given their process of development. Moreover, stable angina management has not been as rigorously evaluated in large randomised trials as other coronary conditions. The role of newer treatment options in management algorithms also merits wider consideration. This expert

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In brief

October 2011 Br J Cardiol 2011;18:203-206

In brief

BJCardio Staff

Abstract

UK cholesterol awareness low Millions of people in the UK hold incorrect beliefs about the risks of cardiovascular disease (CVD), according to HEART UK research. The research, which tested 1,177 people on their knowledge and concerns about high cholesterol, revealed that more than 40% of respondents wrongly thought that raised cholesterol resulted from drinking too much, while almost 60% did not know that the condition can be inherited. Almost half the population have never had a cholesterol check and only 2% of those surveyed named high cholesterol as their biggest health concern. The top health worry for people was cancer, even though CVD i

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May 2010 Br J Cardiol 2010;17:109-10

New NICE guidance on acute coronary syndromes

BJ Cardio Staff

Abstract

They note that although cardiovascular deaths are declining, there were still over 40,000 patients with NSTEMI acute coronary syndromes admitted to hospital in England and Wales in 2009. With worrying increases in the incidence of key risk factors – obesity, diabetes, and the tendency for people to take less exercise – the management of these conditions remains a high priority. As its starting point, the guideline recommends that as soon as a diagnosis of unstable angina or NSTEMI has been made, and aspirin and antithrombin drugs have been offered, patients should be formally assessed for their individual risk of future adverse cardiovasc

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May 2009 Br J Cardiol 2009;16:132–4

Nurse specialist-led management of acute coronary syndromes

Khaled Alfakih, Martin Melville, Jacqui Nainby, Jamie Waterall, Kevin Walters, John Walsh, Alun Harcombe

Abstract

Introduction As the management of patients with acute coronary syndromes (ACS) has changed over recent years, so cardiology services have had to adapt their configurations. We instituted a comprehensive system of nurse specialist-led diagnosis and management of ACS and audited the impact of these changes. The evidence informing our management of ACS patients comes from national registries, such as the prospective registry of acute ischaemic syndrome in the UK (PRAIS-UK)1 and large clinical trials.2-3 The PRAIS-UK registry investigated the management and outcome of 1,046 patients with unstable angina (UA) and non-ST elevation myocardial infarc

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July 2006 Br J Cardiol 2006;13:284-86

Should acute MI patients receive dual antiplatelet therapy: a review of new data

Anthony Gershlick

Abstract

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January 2006 Br J Cardiol 2006;13:9-12

The emerging role of vitamin D and its receptor in the pathogenesis of acute coronary syndromes

Khalid Barakat, Graham A Hitman

Abstract

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November 2005 Br J Cardiol (Acute Interv Cardiol) 2005;12:AIC 81–AIC 82

Percutaneous coronary interventions in West Yorkshire for the year 2002: an audit

Khaled Alfakih, Elizabeth Rennie, Stacey Hunter, James Mclenachan

Abstract

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July 2004 Br J Cardiol (Acute Interv Cardiol) 2004;11:AIC 45–AIC 52

Role of LMWH in ACS, with or without PCI and GP IIb/IIIa blockade

Diana A Gorog, Alamgir MN Kabir, Michael S Marber

Abstract

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September 2003 Br J Cardiol (Acute Interv Cardiol) 2003;10:AIC 75–AIC 77

The use of glycoprotein IIb/IIIa antagonists in acute coronary syndromes: are we following the NICE guidelines?

Julia Baron, Alice V Joy, Sarah Armstrong, Michael Millar-Craig

Abstract

No content available

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