Tag Archives: alteplase

BSH Parliament day Professor Andrew Clark (President of the British Society for Heart Failure) is pictured here (centre) carrying out an echocardiogram in the House of Commons. He was at a BSH event to help raise awareness that a person diagnosed with heart failure is likely to have a worse prognosis than if they were diagnosed with most cancers. This is despite the availability of specialist heart failure services that can have a remarkable impact on a patient’s chance of survival, but for which there is inconsistent access over the UK leading to wide variations in care and outcomes. Over 60 MPs, Peers, and professional and patient groups

This new report from ECASS 3 was published online on October 21st in Lancet Neurology. The authors, led by Dr Werner Hacke (Ruprecht-Karls-Universität, Germany) report that although not all end points were statistically significant, there was “a clear pattern in favour of alteplase”. In the ECASS 3 trial, 821 stroke patients presenting 3-4.5 hours after symptom onset were randomised to alteplase (in the approved regimen of 0.9 mg/kg body weight) or placebo. The primary end point was disability at 90 days, and this was judged by a favourable or unfavourable outcome on the modified Rankin Scale. Results showed that significantly more pati