Tag Archives: cardiac magnetic resonance (CMR)

Introduction Sickle cell disease (SCD) is the most common inherited haematologic disorder in the US, affecting over 100,000 individuals.1,2 In SCD, deoxygenated haemoglobin S (HbS) polymerisation leads to sickling and destruction of red blood cells. Patients experience profound anaemia and vaso-occlusive events. Prolonged capillary inflammation and repeated episodes of ischaemia and reperfusion result in chronic end-organ damage, including the heart and lungs.3 Sickle cell cardiomyopathy contributes to the significant morbidity and mortality among adult patients with SCD. A study by Hamideh and colleagues revealed that 31.6% of total death ce

Introduction In volume overload states, such as aortic regurgitation (AR), ischaemic cardiomyopathy (ICM), and non-ischaemic cardiomyopathy (NICM), spherical dilation occurs.1 Khouri et al. described four remodelling patterns based on the indexed left ventricle (LV) end-diastolic volume and LV concentricity.2 Standard LV chamber quantification, according to the American Society of Echocardiography (ASE) guidelines, involves obtaining a single-dimensional measurement of the LV diameter from the parasternal long-axis acoustic window at the level of mitral valve leaflet tips. Although it is the combination of qualitative and quantitative measure