Tag Archives: diabetes mellitus

Introduction Low-density lipoprotein-cholesterol (LDL-C) is accepted as a causal risk factor for development of atherosclerotic cardiovascular disease (CVD) and acute coronary syndromes (ACS).1 European Society of Cardiology (ESC) guidelines have been extensive in setting up lipid targets for primary and secondary prevention of CVD.2 The 2021 ESC guidelines carry forward the 2019 ESC dyslipidaemia targets to introduce a therapeutic regimen that achieves a ≥50% LDL-C reduction from baseline and a LDL-C goal of <1.4 mmol/L (<55 mg/dL) (very-high-risk group) or <1.8 mmol/L (high-risk group).2 The updated National Institute for Health

Introduction Acute myocardial infarction (AMI) in young patients with systemic inflammatory diseases, such as ulcerative colitis and diabetes mellitus, presents a unique clinical challenge that deviates from traditional cardiovascular risk models. This case aims to highlight the complexities of managing AMI in the presence of systemic inflammation and metabolic disorders, emphasising the need for comprehensive care strategies and a multi-specialty approach for effective management in such cases. The report is relevant to current practice, as it stresses the importance of integrated and interdisciplinary care in managing cardiovascular risk in

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The need for new guidelines The aim of the first guidelines from the Joint British Societies (JBS 1) was to promote a more effective multi-disciplinary approach to cardiovascular disease (CVD) prevention.4 The guidelines addressed the needs of both individuals with established disease and apparently healthy subjects at high risk of developing disease. The National Service Framework for Coronary Heart Disease (CHD) for England and Wales endorsed the lifestyle and risk factor targets in JBS 1.5 It also established national audit standards, which were subsequently reinforced and expanded by the General Medical Services contract for primary care.

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