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Tag Archives: dual antiplatelet therapy (DAPT)

May 2025 Br J Cardiol 2025;32:68–70 doi:10.5837/bjc.2025.021

Proton-pump inhibitors: use and effectiveness in ACS patients receiving dual antiplatelet therapy

Faisal Shehzad, Sundip Patel, Khurram Shahzad, Obi Ikechukwu

Abstract

Introduction Dual antiplatelet therapy (DAPT) comprises a combination of aspirin and thienopyridine agents, such as clopidogrel, prasugrel and ticagrelor. DAPT is the cornerstone of treatment of patients presenting with acute coronary syndrome (ACS), undergoing either medical therapy alone or percutaneous coronary intervention (PCI).1,2 There has been considerable progress in the treatment of ACS with the advent of more potent agents, in addition to therapeutic anticoagulation. DAPT has contributed to improved outcomes in patients presenting with ACS, with numerous studies showing a marked reduction in major adverse cardiovascular and cerebr

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