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Tag Archives: infective endocarditis

May 2019 Br J Cardiol 2019;26:67–8 doi:10.5837/bjc.2019.020

Incidence and epidemiology of infective endocarditis from 2010 to 2017 in a rural UK hospital

Laura A Hughes, Andrew Epstein, Neeraj Prasad

Abstract

Introduction Infective endocarditis (IE) is a relatively rare disease; however, it is becoming increasingly common and is associated with significant morbidity and mortality.1 A recent meta-analysis has revealed that the epidemiology of IE has evolved over the last five decades,2 with significant global variation. Several large epidemiological studies show that the incidence of IE is increasing, particularly in male and elderly patients.3-5 There have also been changes in the microbiology of IE with staphylococci overtaking streptococci as the most frequent causative organism.6 There are few recent studies describing the incidence or epidemio

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British Heart Valve Society update: a change in the NICE guidelines on antibiotic prophylaxis

August 2016 Br J Cardiol 2016;23:91–2 doi:10.5837/bjc.2016.027

British Heart Valve Society update: a change in the NICE guidelines on antibiotic prophylaxis

John B Chambers, Martin H Thornhill, Mark Dayer, David Shanson

Abstract

This change followed approaches to Sir Andrew Dillon by the widow of a patient with a replacement aortic valve who died from infective endocarditis (IE) developing after unprotected dental scaling. Her case included: evidence that antibiotic prophylaxis is effective in people at high risk of IE having high-risk dental procedures;3 the observation that the incidence of IE in the UK has accelerated above the global background rise since the original 2008 NICE guidance;4 a change in the law on consent.5-7  It is now necessary for dentists to appraise their patient of the differences between NICE and other guidelines, if it is likely that they

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Triple-valve infective endocarditis

April 2016 Br J Cardiol 2016;23:65–7 doi:10.5837/bjc.2016.015 Online First

Triple-valve infective endocarditis

Azeem S Sheikh, Asma Abdul Sattar, Claire Williams

Abstract

Introduction Figure 1. Chest X-ray (antero-posterior projection) demonstrating a septic lesion (thick arrow) Despite the significant improvements in both diagnostic and therapeutic procedures in recent years, infective endocarditis (IE) remains a medical challenge due to poor prognosis and high mortality. IE varies according to the initial clinical manifestations, underlying cardiac disease, micro-organisms involved and the associated complications. Echocardiographically, the majority of patients demonstrate vegetations on a single valve, while demonstration of involvement of two valves occurs much less frequently; triple-valve involvement is

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February 2015 Br J Cardiol 2015;22:11 Online First

Correspondence: don’t see their heart broken

Mervyn Huston

Abstract

Dear Sirs, There has been much debate regarding the prophylactic prescribing of antibiotics in patients deemed at risk of developing infective endocarditis (IE) as a result of certain dental procedures.1 The National Institute for Health and Care Excellence (NICE), the British Society for Antimicrobial Chemotherapy (BSAC) and the American Heart Association (AHA) have produced differing guidelines for dental practitioners, who may decide to accept one particular code entirely, or a modified version based on discussion with local cardiology departments. This culture of debate amongst cardiologists, dentists and patients regarding best interest,

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March 2012 Br J Cardiol 2012;19:7–9 doi:10.5837/bjc.2012.002

Endocarditis: the complementary roles of CT and echocardiography

Susanna Price

Abstract

The case study in this issue (see pages 46–7) demonstrates a potential use of CT scanning in the diagnosis of a patient with endocarditis. Electrocardiogram (ECG)-gated multi-detector cardiac computed tomography (MDCT) scanning has been proposed by many to have potential in the evaluation of endocarditis by demonstration of vegetations, complications (coronary artery occlusion, fistulae) and peripheral embolism.3 The major limitations of the technique include availability, spatial resolution, failure to demonstrate leaflet perforations and lack of haemodynamic information (table 1). Further, CT findings have not been correlated with clinica

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March 2012 Br J Cardiol 2012;19:46–7 doi:10.5837/bjc.2012.010

Aortic root fistula complicating infective endocarditis: role of 64-multi-detector CT cardiac angiography

Andrew J Howe, John A Purvis

Abstract

Figure 1. Transoesophageal echocardiogram image. Hollow arrow marks abscess anterior to a bicuspid aortic valve (AV) and below the level of the pulmonary valve (PV). Solid arrow marks vegetation on the posterior aspect of the aortic valve TOE confirmed a 0.8 cm vegetation at the posteriorcommissure of the aortic valve with an ill-defined, 1.6 cm diameter, loculated lesion anterior to the valve pressing into the right ventricular outflow tract. This was felt to be an abscess cavity (hollow arrow, figure 1). TOE showed no involvement or impairment of flow throughout the length of the left main stem (LMS) or proximal right coronary arteries (LMS

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November 2008 Br J Cardiol 2008;15:279-80

Antibiotic prophylaxis against infective endocarditis: new guidelines, new controversy?

Richard G Bogle, Abhay Bajpai

Abstract

NICE guidance The NICE review tried to determine which cardiac conditions are associated with increased risk of IE; whether dental treatment is associated with acute risk of developing the condition and whether ABP was effective in prevention of cases and deaths. The NICE guideline concluded that patients with structural heart disease were at increased risk of IE but did not find convincing evidence that dental ABP was cost-effective. They calculated that if amoxicillin prophylaxis was effective then the cost of preventing a single case of IE would be circa £12 million. In the absence of high-quality evidence for clinical effectiveness the

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March 2007 Br J Cardiol 2007;14:109

Infective endocarditis with secondary lesions in the pinna

Akeel Jubber, Hon Shing Ong, Yoganathan Suthahar, Ravinder Randhawa

Abstract

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