August 2025 Br J Cardiol 2025;32(3) doi:10.5837/bjc.2025.037 Online First
Miriam Jassam Walker, Gowri Sri Paranthaman, Haqeel Jamil
Introduction Platypnea-orthodeoxia syndrome (POS) is a rare condition, the prevalence of which has yet to be estimated in the literature.1 It presents with positional dyspnoea and deoxygenation on an orthopneic position which resolves when the patient moves to a supine position. Diagnosis is often challenging and this syndrome is thought to be under-recognised.2 Its mechanisms are not fully understood but these can be classified into extracardiac and intracardiac causes. Extracardiac causes include pathology leading to intrapulmonary shunting or ventilation-perfusion mismatch, such as pulmonary arteriovenous malformations or severe intestinal
October 2011 Br J Cardiol 2011;18:219–22 doi:10.5837/bjc.2011.002
Sudhakar George, David Hildick-Smith
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Jessica Wilson, Paul Oldershaw
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