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News from the Cardiorenal Forum 12th Annual Scientific Meeting – Improving treatments in cardiorenal patients

March 2018

News from the Cardiorenal Forum 12th Annual Scientific Meeting – Improving treatments in cardiorenal patients

Fazlullah Wardak and Rosie Kalsi

Abstract

Do new diabetes drugs protect the heart and kidney? The day’s keynote session was given by Professor Johannes Mann (Friedrich Alexander University of Erlangen, Germany). Diabetes management has been transformed with the introduction of newer agents with the promise of cardiovascular and renal protection. The sodium glucose co-transporter-2 (SGLT-2) inhibitors are known to reduce the hyperfiltration, which occurs in early diabetic nephropathy. Glucagon-like peptide 1 (GLP-1) receptor agonists are incretin mimetics, which have several benefits for diabetes management. The mechanisms by which GLP-1 agonist therapy may reduce blood pressur

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December 2017

Hyperkalaemia: who gets it, how frequent is it, what do I do and does it matter?

Professor David Wheeler, Dr Colin Doig

Abstract

Hyperkalaemia is often multifactorial in origin and may be seen in chronic kidney disease (CKD), acute kidney injury, heart failure, diabetes, elderly patients and those prescribed renin-angiotensin-aldosterone-system (RAAS) antagonists. This important area is often somewhat neglected by healthcare professionals. Left untreated, high potassium increases the risk of mortality in CKD and can also result in increased risk of serious cardiac arrhythmia and other acute complications. Chronically it may result in patients with heart failure having symptom and life-improving treatments withdrawn. New therapies for hyperkalaemia are now coming throu

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News from the Cardiorenal Forum 9th Annual Scientific Meeting – embracing the future, not forgetting the past

March 2015 Br J Cardiol 2015;22:17

News from the Cardiorenal Forum 9th Annual Scientific Meeting – embracing the future, not forgetting the past

Dr Legate Philip

Abstract

Managing risk factors – the old offenders Diet An update on diet and cardiovascular disease was given by Professor Kay Tee Khaw (University of Cambridge). A surprise recent finding has been that increased body mass index (BMI) trends do not directly correlate with cardiovascular mortality, particularly in Mediterranean countries (figure 1). Figure 1. Body mass index and associated coronary heart disease in Europe. Panel a) body mass index; panel b) coronary heart disease This gives rise to the question: is diet a key moderating factor in the relationship between BMI and cardiovascular mortality? The PREDIMED (Effects of the Mediterranean Di

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News from the 7th Annual Scientific Meeting of the Cardiorenal Forum

December 2012 Br J Cardiol 2013;20:20–1 Online First

News from the 7th Annual Scientific Meeting of the Cardiorenal Forum

Abstract

Introduction As doctors and scientists we are accustomed to breaking down problems and simplifying complex pathology in order to focus our management and identify possible targets for future therapies. The pathophysiology of cardiorenal disease is no different but, as yet, attempts to elucidate the complex interaction between heart and kidneys has failed. Although cardiac and renal disease are often diagnosed together, it is clear that a straightforward causal relationship does not exist. Disease in either serves as a risk factor for disease in the other and perpetuates the progression of that disease, but why this is so is unclear. Whilst th

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